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KMID : 1040320210280010042
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Pediatric Infection & Vaccine
2021 Volume.28 No. 1 p.42 ~ p.48
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A Case with Multiple Fungal Coinfections in a Patient who Presented with Pancoast Syndrome
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Jin Hyung-Suk
Kim Dong-Sub
Choi Joon-Sik
Huh Hee-Jae
Lee Nam-Yong
Han Joung-Ho
Cho Hee-Won
Ma Young-Eun
Jeon Tae-Yeon
Yoo So-Young
Yoo Keon-Hee
Koo Hong-Hoe
Kim Yae-Jean
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Abstract
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Invasive fungal infection (IFI) is a serious threat to pediatric patients with cancer given high morbidity and mortality. We present an 18-year-old male with precursor T-cell lymphoblastic leukemia who developed Pancoast syndrome, presented with paresthesia and numbness in the right shoulder and arm during a neutropenic fever period. He was diagnosed with pneumonia in the right upper lung field. He was later found to have an invasive pulmonary fungal infection caused by multiple fungi species, including Rhizomucor, confirmed by histology and polymerase chain reaction (PCR) (proven infection), Penicillium decumbens diagnosed by PCR, and Aspergillus suspected from galactomannan assay (probable infection). Unfortunately, the patient's condition further worsened owing to the aggravation of leukemia, chemotherapy-induced neutropenia, and bacterial coinfection, leading to multiorgan failure and death. Here, we report a case of IFI caused by multiple fungal species that presented as Pancoast syndrome.
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KEYWORD
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Pancoast syndrome, Lung diseases, fungal, Coinfection
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